Pharmacological exploitation of the phenothiazine antipsychotics to develop novel antitumor agents–A drug repurposing strategy

Phenothiazines (PTZs) have been used for the antipsychotic drugs for centuries. However, some of these PTZs have been reported to exhibit antitumor effects by targeting various signaling pathways in vitro and in vivo. Thus, this study was aimed at exploiting trifluoperazine, one of PTZs, to develop...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Hsien, Bai, Li-Yuan, Tsai, Ming-Hsui, Chu, Po-Chen, Chiu, Chang-Fang, Chen, Michael Yuanchien, Chiu, Shih-Jiuan, Chiang, Jo-Hua, Weng, Jing-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899727/
https://www.ncbi.nlm.nih.gov/pubmed/27277973
http://dx.doi.org/10.1038/srep27540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899727/
https://www.ncbi.nlm.nih.gov/pubmed/27277973
http://dx.doi.org/10.1038/srep27540

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