The PD-1/PD-L1 inhibitory pathway is altered in pre-eclampsia and regulates T cell responses in pre-eclamptic rats

The programmed cell death-1(PD-1)/PD-ligand 1 (PD-L1) pathway is critical to immune homeostasis by promoting regulatory T (Treg) development and inhibiting effector T (such as Th17) cell responses. However, the association between the PD-1/PD-L1 pathway and the Treg/Th17 imbalance has not been fully...

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Detalles Bibliográficos
Autores principales: Tian, Mei, Zhang, Yonghong, Liu, Zhaozhao, Sun, Guoqiang, Mor, Gil, Liao, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899740/
https://www.ncbi.nlm.nih.gov/pubmed/27277012
http://dx.doi.org/10.1038/srep27683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899740/
https://www.ncbi.nlm.nih.gov/pubmed/27277012
http://dx.doi.org/10.1038/srep27683

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