Optimal Trend Tests for Genetic Association Studies of Heterogeneous Diseases

The Cochran-Armitage trend test is a standard procedure in genetic association studies. It is a directed test with high power to detect genetic effects that follow the gene-dosage model. In this paper, the author proposes optimal trend tests for genetic association studies of heterogeneous diseases....

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Detalles Bibliográficos
Autor principal: Lee, Wen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899796/
https://www.ncbi.nlm.nih.gov/pubmed/27278756
http://dx.doi.org/10.1038/srep27821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899796/
https://www.ncbi.nlm.nih.gov/pubmed/27278756
http://dx.doi.org/10.1038/srep27821

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