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Optimal Trend Tests for Genetic Association Studies of Heterogeneous Diseases
The Cochran-Armitage trend test is a standard procedure in genetic association studies. It is a directed test with high power to detect genetic effects that follow the gene-dosage model. In this paper, the author proposes optimal trend tests for genetic association studies of heterogeneous diseases....
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899796/ https://www.ncbi.nlm.nih.gov/pubmed/27278756 http://dx.doi.org/10.1038/srep27821 |