Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification

ATP production requires the establishment of an electrochemical proton gradient across the inner mitochondrial membrane. Mitochondrial uncouplers dissipate this proton gradient and disrupt numerous cellular processes, including vesicular trafficking, mainly through energy depletion. Here we show tha...

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Detalles Bibliográficos
Autores principales: Dejonghe, Wim, Kuenen, Sabine, Mylle, Evelien, Vasileva, Mina, Keech, Olivier, Viotti, Corrado, Swerts, Jef, Fendrych, Matyáš, Ortiz-Morea, Fausto Andres, Mishev, Kiril, Delang, Simon, Scholl, Stefan, Zarza, Xavier, Heilmann, Mareike, Kourelis, Jiorgos, Kasprowicz, Jaroslaw, Nguyen, Le Son Long, Drozdzecki, Andrzej, Van Houtte, Isabelle, Szatmári, Anna-Mária, Majda, Mateusz, Baisa, Gary, Bednarek, Sebastian York, Robert, Stéphanie, Audenaert, Dominique, Testerink, Christa, Munnik, Teun, Van Damme, Daniël, Heilmann, Ingo, Schumacher, Karin, Winne, Johan, Friml, Jiří, Verstreken, Patrik, Russinova, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899852/
https://www.ncbi.nlm.nih.gov/pubmed/27271794
http://dx.doi.org/10.1038/ncomms11710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899852/
https://www.ncbi.nlm.nih.gov/pubmed/27271794
http://dx.doi.org/10.1038/ncomms11710

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