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The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells
BACKGROUND: Resistance to taxane-based therapy in breast cancer patients is a major clinical problem that may be addressed through insight of the genomic alterations leading to taxane resistance in breast cancer cells. In the current study we used whole exome sequencing to discover somatic genomic a...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899892/ https://www.ncbi.nlm.nih.gov/pubmed/27277198 http://dx.doi.org/10.1186/s12864-016-2749-4 |