The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

BACKGROUND: Resistance to taxane-based therapy in breast cancer patients is a major clinical problem that may be addressed through insight of the genomic alterations leading to taxane resistance in breast cancer cells. In the current study we used whole exome sequencing to discover somatic genomic a...

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Detalles Bibliográficos
Autores principales: Hansen, Stine Ninel, Ehlers, Natasja Spring, Zhu, Shida, Thomsen, Mathilde Borg Houlberg, Nielsen, Rikke Linnemann, Liu, Dongbing, Wang, Guangbiao, Hou, Yong, Zhang, Xiuqing, Xu, Xun, Bolund, Lars, Yang, Huanming, Wang, Jun, Moreira, Jose, Ditzel, Henrik J, Brünner, Nils, Schrohl, Anne-Sofie, Stenvang, Jan, Gupta, Ramneek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899892/
https://www.ncbi.nlm.nih.gov/pubmed/27277198
http://dx.doi.org/10.1186/s12864-016-2749-4

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