Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington’s Disease Mice

Background: Dysregulation of iron homeostasis is implicated in the pathogenesis of Huntington’s disease. We have previously shown that increased iron intake in R6/2 HD neonatal mice, but not adult R6/2 HD mice potentiates disease outcomes at 12-weeks of age corresponding to advanced HD [Redox Biol....

Descripción completa

Detalles Bibliográficos
Autores principales: Berggren, Kiersten L., Lu, Zhen, Fox, Julia A., Dudenhoeffer, Megan, Agrawal, Sonal, Fox, Jonathan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899980/
https://www.ncbi.nlm.nih.gov/pubmed/27079948
http://dx.doi.org/10.3233/JHD-150182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899980/
https://www.ncbi.nlm.nih.gov/pubmed/27079948
http://dx.doi.org/10.3233/JHD-150182

Ejemplares similares