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Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignancies

PURPOSE OF REVIEW: The CARMA1/BCL10/MALT1 (CBM) complex is a multimeric signaling complex controlling several important aspects of lymphocyte activation. Gain-of-function mutations in the genes encoding CBM proteins or their upstream regulators are associated with lymphoid malignancies, whereas loss...

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Detalles Bibliográficos
Autores principales: Juilland, Mélanie, Thome, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams And Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900422/
https://www.ncbi.nlm.nih.gov/pubmed/27135977
http://dx.doi.org/10.1097/MOH.0000000000000257