Cargando…

Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignancies

PURPOSE OF REVIEW: The CARMA1/BCL10/MALT1 (CBM) complex is a multimeric signaling complex controlling several important aspects of lymphocyte activation. Gain-of-function mutations in the genes encoding CBM proteins or their upstream regulators are associated with lymphoid malignancies, whereas loss...

Descripción completa

Detalles Bibliográficos
Autores principales:	Juilland, Mélanie, Thome, Margot
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams And Wilkins 2016
Materias:	LYMPHOID BIOLOGY AND DISEASES: Edited by Ari M. Melnick
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900422/ https://www.ncbi.nlm.nih.gov/pubmed/27135977 http://dx.doi.org/10.1097/MOH.0000000000000257

Ejemplares similares

New insights into redox homeostasis as a therapeutic target in B-cell malignancies
por: Graczyk-Jarzynka, Agnieszka, et al.
Publicado: (2017)

Holding All the CARDs: How MALT1 Controls CARMA/CARD-Dependent Signaling
por: Juilland, Mélanie, et al.
Publicado: (2018)

MALT1 protease activity in primary effusion lymphoma
por: Juilland, Mélanie, et al.
Publicado: (2017)

IκB kinase β–induced phosphorylation of CARMA1 contributes to CARMA1–Bcl10–MALT1 complex formation in B cells
por: Shinohara, Hisaaki, et al.
Publicado: (2007)

Structural Insights into the Assembly of CARMA1 and BCL10
por: Li, Siwei, et al.
Publicado: (2012)

Characteristics of CARMA1-BCL10-MALT1-A20-NF-κB expression in T cell-acute lymphocytic leukemia
por: Ma, Yu, et al.
Publicado: (2014)

AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-κB signaling upon T cell activation
por: Schimmack, Gisela, et al.
Publicado: (2014)

The CARMA3-BCL10-MALT1 (CBM) complex contributes to DNA damage-induced NF-κB activation and cell survival
por: Zhang, Shilei, et al.
Publicado: (2017)

Predictors of survival in patients with MALT lymphoma: a retrospective, case-control study
por: Qi, Shunan, et al.
Publicado: (2022)

CXCL12/SDF-1α Activates NF-κB and Promotes Oral Cancer Invasion through the Carma3/Bcl10/Malt1 Complex
por: Rehman, Aasia O, et al.
Publicado: (2009)

Post-translational Modifications of the CARMA1-BCL10-MALT1 Complex in Lymphocytes and Activated B-Cell Like Subtype of Diffuse Large B-Cell Lymphoma
por: Thys, An, et al.
Publicado: (2018)

Diffuse large B-cell lymphomas in adults with aberrant coexpression of CD10, BCL6, and MUM1 are enriched in IRF4 rearrangements
por: Frauenfeld, Leonie, et al.
Publicado: (2022)

Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies
por: Thomalla, D., et al.
Publicado: (2022)

Decreased IL-10 accelerates B-cell leukemia/lymphoma in a mouse model of pediatric lymphoid leukemia
por: Fitch, Briana A., et al.
Publicado: (2022)

Immunodeficiency and CARD-BCL10-MALT1
por: Pérez de Diego, Rebeca
Publicado: (2015)

Heterogeneous modulation of Bcl-2 family members and drug efflux mediate MCL-1 inhibitor resistance in multiple myeloma
por: Bolomsky, Arnold, et al.
Publicado: (2021)

Aberrant expression of GOLM1 protects ALK(+) anaplastic large cell lymphoma from apoptosis by enhancing BCL-X(L) stability
por: Zi, Zhenguo, et al.
Publicado: (2023)

Clonotype pattern in T-cell lymphomas map the cell of origin to immature lymphoid precursors
por: Iyer, Aishwarya, et al.
Publicado: (2022)

Molecular architecture and regulation of BCL10-MALT1 filaments
por: Schlauderer, Florian, et al.
Publicado: (2018)

Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the gallbladder and review of the literature
por: Honda, Munenori, et al.
Publicado: (2017)

The paracaspase MALT1: biological function and potential for therapeutic inhibition
por: Jaworski, Maike, et al.
Publicado: (2015)

PRMT5 inhibition drives therapeutic vulnerability to combination treatment with BCL-2 inhibition in mantle cell lymphoma
por: Brown-Burke, Fiona, et al.
Publicado: (2023)

The TΑp63/BCL2 axis represents a novel mechanism of clinical aggressiveness in chronic lymphocytic leukemia
por: Laidou, Stamatia, et al.
Publicado: (2022)

Cytotoxicity of the CD3×CD20 bispecific antibody epcoritamab in CLL is increased by concurrent BTK or BCL-2 targeting
por: Mhibik, Maissa, et al.
Publicado: (2023)

Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2(+) diffuse large B-cell lymphomas
por: Shen, Yajie, et al.
Publicado: (2022)

CXCR4 PET/MRI for follow-up of gastric mucosa–associated lymphoid tissue lymphoma after first-line Helicobacter pylori eradication
por: Mayerhoefer, Marius E., et al.
Publicado: (2022)

BCL10GFP fusion protein as a substrate for analysis of determinants required for Mucosa-Associated Lymphoid Tissue 1 (MALT1)-mediated cleavage
por: Jou, Shin-Yi, et al.
Publicado: (2012)

SBNO2 is a critical mediator of STAT3-driven hematological malignancies
por: Brandstoetter, Tania, et al.
Publicado: (2023)

JAK/STAT blockade reverses the malignant phenotype of Hodgkin and Reed-Sternberg cells
por: Fernández, Sara, et al.
Publicado: (2022)

A germinal center–associated microenvironmental signature reflects malignant phenotype and outcome of DLBCL
por: Miyawaki, Kohta, et al.
Publicado: (2022)

Comparing the value of mono- vs coculture for high-throughput compound screening in hematological malignancies
por: Herbst, Sophie A., et al.
Publicado: (2023)

NUDT15 variants confer high incidence of second malignancies in children with acute lymphoblastic leukemia
por: Yoshida, Masanori, et al.
Publicado: (2021)

A Multi-Center Retrospective Review of COVID-19 Outcomes in Patients with Lymphoid Malignancy
por: Choi, Yun, et al.
Publicado: (2021)

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL
por: Antoszewski, Mateusz, et al.
Publicado: (2022)

Generation of a humanized afucosylated BAFF-R antibody with broad activity against human B-cell malignancies
por: Dong, Zhenyuan, et al.
Publicado: (2022)

First‐line antibiotic treatment in patients with localized extragastric mucosa‐associated lymphoid tissue lymphoma
por: Yao, Ming, et al.
Publicado: (2022)

Incidence and time trends of second primary malignancies after non-Hodgkin lymphoma: a Swedish population-based study
por: Joelsson, Joel, et al.
Publicado: (2022)

V-CARMA: A tool for the detection and modification of antigen-specific T cells
por: Guo, Xi-zhi J., et al.
Publicado: (2022)

USP1 promotes the aerobic glycolysis and progression of T-cell acute lymphoblastic leukemia via PLK1/LDHA axis
por: Liu, Shuguang, et al.
Publicado: (2023)

SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia
por: Brown, Lauren M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ba2ka6rgao6saonh3t8nlkoki6