Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration

The selenoenzyme glutathione peroxidase 4 (Gpx4) is an essential mammalian glutathione peroxidase, which protects cells against detrimental lipid peroxidation and governs a novel form of regulated necrotic cell death, called ferroptosis. To study the relevance of Gpx4 and of another vitally importan...

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Detalles Bibliográficos
Autores principales: Carlson, Bradley A., Tobe, Ryuta, Yefremova, Elena, Tsuji, Petra A., Hoffmann, Victoria J., Schweizer, Ulrich, Gladyshev, Vadim N., Hatfield, Dolph L., Conrad, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900515/
https://www.ncbi.nlm.nih.gov/pubmed/27262435
http://dx.doi.org/10.1016/j.redox.2016.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900515/
https://www.ncbi.nlm.nih.gov/pubmed/27262435
http://dx.doi.org/10.1016/j.redox.2016.05.003

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