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Leishmania major Promastigotes Evade LC3-Associated Phagocytosis through the Action of GP63

The protozoan Leishmania parasitizes macrophages and evades the microbicidal consequences of phagocytosis through the inhibition of phagolysosome biogenesis. In this study, we investigated the impact of this parasite on LC3-associated phagocytosis, a non-canonical autophagic process that enhances ph...

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Detalles Bibliográficos
Autores principales: Matte, Christine, Casgrain, Pierre-André, Séguin, Olivier, Moradin, Neda, Hong, Wan Jin, Descoteaux, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900527/
https://www.ncbi.nlm.nih.gov/pubmed/27280768
http://dx.doi.org/10.1371/journal.ppat.1005690