FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1

The intracellular amino acid pool within lysosome is a signal that stimulates the nutrient-sensing mTORC1 signalling pathway. The signal transduction cascade has garnered much attention, but little is known about the sequestration of the signalling molecules within the lysosome. Using human HEK293 c...

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Detalles Bibliográficos
Autores principales: Wu, Xiaochun, Zhao, Lingling, Chen, Zhi, Ji, Xin, Qiao, Xianfeng, Jin, Yaping, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900541/
https://www.ncbi.nlm.nih.gov/pubmed/27280402
http://dx.doi.org/10.1371/journal.pone.0157100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900541/
https://www.ncbi.nlm.nih.gov/pubmed/27280402
http://dx.doi.org/10.1371/journal.pone.0157100

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