Cargando…

Investigation of NS3 Protease Resistance-Associated Variants and Phenotypes for the Prediction of Treatment Response to HCV Triple Therapy

Triple therapy of chronic hepatitis C virus (HCV) infection with boceprevir (BOC) or telaprevir (TVR) leads to virologic failure in many patients which is often associated with the selection of resistance-associated variants (RAVs). These resistance profiles are of importance for the selection of po...

Descripción completa

Detalles Bibliográficos
Autores principales: Dietz, Julia, Rupp, Daniel, Susser, Simone, Vermehren, Johannes, Peiffer, Kai-Henrik, Filmann, Natalie, Bon, Dimitra, Kuntzen, Thomas, Mauss, Stefan, Grammatikos, Georgios, Perner, Dany, Berkowski, Caterina, Herrmann, Eva, Zeuzem, Stefan, Bartenschlager, Ralf, Sarrazin, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900565/
https://www.ncbi.nlm.nih.gov/pubmed/27281344
http://dx.doi.org/10.1371/journal.pone.0156731