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Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment

Receptor-targeted lentiviral vectors (LVs) can be an effective tool for selective transfer of genes into distinct cell types of choice. Moreover, they can be used to determine the molecular properties that cell surface proteins must fulfill to act as receptors for viral glycoproteins. Here we show t...

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Detalles Bibliográficos
Autores principales: Bender, Ruben R., Muth, Anke, Schneider, Irene C., Friedel, Thorsten, Hartmann, Jessica, Plückthun, Andreas, Maisner, Andrea, Buchholz, Christian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900575/
https://www.ncbi.nlm.nih.gov/pubmed/27281338
http://dx.doi.org/10.1371/journal.ppat.1005641