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CDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following Mitosis
Cell proliferation is driven by cyclical activation of cyclin-dependent kinases (CDKs), which produce distinct biochemical cell cycle phases. Mitosis (M phase) is orchestrated by CDK-1, complexed with mitotic cyclins. During M phase, chromosomes are segregated by a bipolar array of microtubules call...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900577/ https://www.ncbi.nlm.nih.gov/pubmed/27281342 http://dx.doi.org/10.1371/journal.pone.0157491 |