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Mutations Affecting Potassium Import Restore the Viability of the Escherichia coli DNA Polymerase III holD Mutant

Mutants lacking the ψ (HolD) subunit of the Escherichia coli DNA Polymerase III holoenzyme (Pol III HE) have poor viability, but a residual growth allows the isolation of spontaneous suppressor mutations that restore ΔholD mutant viability. Here we describe the isolation and characterization of two...

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Detalles Bibliográficos
Autores principales: Durand, Adeline, Sinha, Anurag Kumar, Dard-Dascot, Cloelia, Michel, Bénédicte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900610/
https://www.ncbi.nlm.nih.gov/pubmed/27280472
http://dx.doi.org/10.1371/journal.pgen.1006114