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Dihydrostreptomycin Directly Binds to, Modulates, and Passes through the MscL Channel Pore
The primary mechanism of action of the antibiotic dihydrostreptomycin is binding to and modifying the function of the bacterial ribosome, thus leading to decreased and aberrant translation of proteins; however, the routes by which it enters the bacterial cell are largely unknown. The mechanosensitiv...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900634/ https://www.ncbi.nlm.nih.gov/pubmed/27280286 http://dx.doi.org/10.1371/journal.pbio.1002473 |