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The Race against Protease Activation Defines the Role of ESCRTs in HIV Budding

HIV virions assemble on the plasma membrane and bud out of infected cells using interactions with endosomal sorting complexes required for transport (ESCRTs). HIV protease activation is essential for maturation and infectivity of progeny virions, however, the precise timing of protease activation an...

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Detalles Bibliográficos
Autores principales: Bendjennat, Mourad, Saffarian, Saveez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900648/
https://www.ncbi.nlm.nih.gov/pubmed/27280284
http://dx.doi.org/10.1371/journal.ppat.1005657