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Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil Migration

For efficient polarity and migration, cells need to regulate the magnitude and spatial distribution of actin assembly. This process is coordinated by reciprocal interactions between the actin cytoskeleton and mechanical forces. Actin polymerization-based protrusion increases tension in the plasma me...

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Detalles Bibliográficos
Autores principales: Diz-Muñoz, Alba, Thurley, Kevin, Chintamen, Sana, Altschuler, Steven J., Wu, Lani F., Fletcher, Daniel A., Weiner, Orion D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900667/
https://www.ncbi.nlm.nih.gov/pubmed/27280401
http://dx.doi.org/10.1371/journal.pbio.1002474