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Remodeling of B-Cell Subsets in Blood during Pegylated IFNα-2a Therapy in Patients with Chronic Hepatitis B Infection

The ultimate goal of pegylated interferon-alfa-2a (Peg-IFN-α) therapy in chronic hepatitis B (CHB) infection is HBsAg seroconversion. Even though B cells are major mediators of a positive clinical outcome, their modulation during Peg-IFN-α therapy has not yet been described. We investigated here the...

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Detalles Bibliográficos
Autores principales: Aspord, Caroline, Bruder Costa, Juliana, Jacob, Marie-Christine, Dufeu-Duchesne, Tania, Bertucci, Inga, Pouget, Noelle, Brevot-Lutton, Ophelie, Zoulim, Fabien, Bourliere, Marc, Plumas, Joel, Leroy, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900671/
https://www.ncbi.nlm.nih.gov/pubmed/27281019
http://dx.doi.org/10.1371/journal.pone.0156200