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Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production

Mitochondrial transcription factor A (TFAM) had previously been shown to act as a damage associated molecular pattern with the ability to enhance CpG-A phosphorothioate oligodeoxynucleotide (ODN)-mediated stimulation of IFNα production from human plasmacytoid dendritic cells. Examination of the mech...

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Detalles Bibliográficos
Autores principales: Malarkey, Christopher S., Gustafson, Claire E., Saifee, Jessica F., Torres, Raul M., Churchill, Mair E. A., Janoff, Edward N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900672/
https://www.ncbi.nlm.nih.gov/pubmed/27280778
http://dx.doi.org/10.1371/journal.pone.0157157