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How to move an amphipathic molecule across a lipid bilayer: different mechanisms for different ABC transporters?

Import of β-oxidation substrates into peroxisomes is mediated by ATP binding cassette (ABC) transporters belonging to subfamily D. In order to enter the β-oxidation pathway, fatty acids are activated by conversion to fatty acyl-CoA esters, a reaction which is catalysed by acyl-CoA synthetases (ACSs)...

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Detalles Bibliográficos
Autores principales: Theodoulou, Frederica L., Carrier, David J., Schaedler, Theresia A., Baldwin, Stephen A., Baker, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900756/
https://www.ncbi.nlm.nih.gov/pubmed/27284041
http://dx.doi.org/10.1042/BST20160040