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Spatiotemporal interplay of severe acute respiratory syndrome coronavirus and respiratory mucosal cells drives viral dissemination in rhesus macaques

Innate immune responses have a critical role in the control of early virus replication and dissemination. It remains unknown, however, how severe acute respiratory syndrome coronavirus (SARS-CoV) evades respiratory innate immunity to establish a systemic infection. Here we show in Chinese macaques t...

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Detalles Bibliográficos
Autores principales: Liu, L, Wei, Q, Nishiura, K, Peng, J, Wang, H, Midkiff, C, Alvarez, X, Qin, C, Lackner, A, Chen, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Society for Mucosal Immunology. Published by Elsevier Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900951/
https://www.ncbi.nlm.nih.gov/pubmed/26647718
http://dx.doi.org/10.1038/mi.2015.127