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Early Treatment with Basal Insulin Glargine in People with Type 2 Diabetes: Lessons from ORIGIN and Other Cardiovascular Trials

Dysglycemia results from a deficit in first-phase insulin secretion compounded by increased insulin insensitivity, exposing β cells to chronic hyperglycemia and excessive glycemic variability. Initiation of intensive insulin therapy at diagnosis of type 2 diabetes mellitus (T2DM) to achieve normogly...

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Detalles Bibliográficos
Autores principales: Hanefeld, Markolf, Monnier, Louis, Schnell, Oliver, Owens, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900970/
https://www.ncbi.nlm.nih.gov/pubmed/26861811
http://dx.doi.org/10.1007/s13300-016-0153-3