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Emerging Roles of the Mitogen and Stress Activated Kinases MSK1 and MSK2

Mitogen- and stress-activated kinases (MSK) 1 and 2 are nuclear proteins activated downstream of the ERK1/2 or p38 MAPK pathways. MSKs phosphorylate multiple substrates, including CREB and Histone H3, and their major role is the regulation of specific subsets of Immediate Early genes (IEG). While MS...

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Detalles Bibliográficos
Autores principales: Reyskens, Kathleen M. S. E., Arthur, J. Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901046/
https://www.ncbi.nlm.nih.gov/pubmed/27376065
http://dx.doi.org/10.3389/fcell.2016.00056