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Long-Term Estrogen Receptor Beta Agonist Treatment Modifies the Hippocampal Transcriptome in Middle-Aged Ovariectomized Rats

Estradiol (E2) robustly activates transcription of a broad array of genes in the hippocampal formation of middle-aged ovariectomized rats via estrogen receptors (ERα, ERβ, and G protein-coupled ER). Selective ERβ agonists also influence hippocampal functions, although their downstream molecular targ...

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Detalles Bibliográficos
Autores principales: Sárvári, Miklós, Kalló, Imre, Hrabovszky, Erik, Solymosi, Norbert, Rodolosse, Annie, Liposits, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901073/
https://www.ncbi.nlm.nih.gov/pubmed/27375434
http://dx.doi.org/10.3389/fncel.2016.00149