Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening Methodologies

HIGHLIGHTS: Many CNS targets are being explored for multi-target drug design. New databases and cheminformatic methods enable prediction of primary pharmaceutical target and off-targets of compounds. QSAR, virtual screening and docking methods increase the potential of rational drug design. The dive...

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Detalles Bibliográficos
Autores principales: Nikolic, Katarina, Mavridis, Lazaros, Djikic, Teodora, Vucicevic, Jelica, Agbaba, Danica, Yelekci, Kemal, Mitchell, John B. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901078/
https://www.ncbi.nlm.nih.gov/pubmed/27375423
http://dx.doi.org/10.3389/fnins.2016.00265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901078/
https://www.ncbi.nlm.nih.gov/pubmed/27375423
http://dx.doi.org/10.3389/fnins.2016.00265

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