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Glucocorticoid receptor polymorphisms modulate cardiometabolic risk factors in patients in long-term remission of Cushing’s syndrome

CONTEXT: Glucocorticoid receptor (GR) polymorphisms modulate glucocorticoid (GC) sensitivity and are associated with altered metabolic profiles. OBJECTIVE: To evaluate the presence of GR polymorphisms (BclI (rs41423247), N363S (rs56149945), ER22/23EK (rs6189/rs6190), and 9β (rs6198) and investigate...

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Detalles Bibliográficos
Autores principales: Roerink, Sean H. P. P., Wagenmakers, M. A. E. M., Smit, J. W. A., van Rossum, E. F. C., Netea-Maier, R. T., Plantinga, T. S., Hermus, A. R. M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901092/
https://www.ncbi.nlm.nih.gov/pubmed/26873309
http://dx.doi.org/10.1007/s12020-016-0883-z