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Estimating cumulative risks for breast cancer for carriers of variants in uncommon genes
The rapid clinical embrace of next generation multigene cancer predisposition panels has resulted in discovery of DNA variants in genes for which very limited data on penetrance has been published. Evidence for increased risks associated with these genes is often expressed in odds ratios and studies...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901094/ https://www.ncbi.nlm.nih.gov/pubmed/26960971 http://dx.doi.org/10.1007/s10689-016-9896-2 |