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Estimating cumulative risks for breast cancer for carriers of variants in uncommon genes

The rapid clinical embrace of next generation multigene cancer predisposition panels has resulted in discovery of DNA variants in genes for which very limited data on penetrance has been published. Evidence for increased risks associated with these genes is often expressed in odds ratios and studies...

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Detalles Bibliográficos
Autores principales: Lindor, Noralane M., Hopper, John, Dowty, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901094/
https://www.ncbi.nlm.nih.gov/pubmed/26960971
http://dx.doi.org/10.1007/s10689-016-9896-2