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Islet-intrinsic effects of CFTR mutation

Cystic fibrosis-related diabetes (CFRD) is the most significant extra-pulmonary comorbidity in cystic fibrosis (CF) patients, and accelerates lung decline. In addition to the traditional view that CFRD is a consequence of fibrotic destruction of the pancreas as a whole, emerging evidence may implica...

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Detalles Bibliográficos
Autores principales: Koivula, Fiona N. Manderson, McClenaghan, Neville H., Harper, Alan G. S., Kelly, Catriona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901107/
https://www.ncbi.nlm.nih.gov/pubmed/27033560
http://dx.doi.org/10.1007/s00125-016-3936-1