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Differential regulation of serum microRNA expression by HNF1β and HNF1α transcription factors

AIMS/HYPOTHESIS: We aimed to identify microRNAs (miRNAs) under transcriptional control of the HNF1β transcription factor, and investigate whether its effect manifests in serum. METHODS: The Polish cohort (N = 60) consisted of 11 patients with HNF1B-MODY, 17 with HNF1A-MODY, 13 with GCK-MODY, an HbA(...

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Detalles Bibliográficos
Autores principales: Fendler, Wojciech, Madzio, Joanna, Kozinski, Kamil, Patel, Kashyap, Janikiewicz, Justyna, Szopa, Magdalena, Tracz, Adam, Borowiec, Maciej, Jarosz-Chobot, Przemyslawa, Mysliwiec, Malgorzata, Szadkowska, Agnieszka, Hattersley, Andrew T., Ellard, Sian, Malecki, Maciej T., Dobrzyn, Agnieszka, Mlynarski, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901123/
https://www.ncbi.nlm.nih.gov/pubmed/27059371
http://dx.doi.org/10.1007/s00125-016-3945-0