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Beneficial effect of feeding a ketogenic diet to mothers on brain development in their progeny with a murine model of pyruvate dehydrogenase complex deficiency

Pyruvate dehydrogenase complex (PDC) deficiency is a major inborn error of oxidative metabolism of pyruvate in the mitochondria causing congenital lactic acidosis and primarily structural and functional abnormalities of the central nervous system. To provide an alternate source of acetyl-CoA derived...

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Detalles Bibliográficos
Autores principales: Pliss, Lioudmila, Jatania, Urvi, Patel, Mulchand S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901178/
https://www.ncbi.nlm.nih.gov/pubmed/27331005
http://dx.doi.org/10.1016/j.ymgmr.2016.03.012