Discovery of novel peptides targeting pro-atherogenic endothelium in disturbed flow regions -Targeted siRNA delivery to pro-atherogenic endothelium in vivo

Atherosclerosis occurs preferentially in arterial regions exposed to disturbed blood flow. Targeting these pro-atherogenic regions is a potential anti-atherogenic therapeutic approach, but it has been extremely challenging. Here, using in vivo phage display approach and the partial carotid ligation...

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Detalles Bibliográficos
Autores principales: Chung, Jihwa, Shim, Hyunbo, Kim, Kwanchang, Lee, Duhwan, Kim, Won Jong, Kang, Dong Hoon, Kang, Sang Won, Jo, Hanjoong, Kwon, Kihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901192/
https://www.ncbi.nlm.nih.gov/pubmed/27173134
http://dx.doi.org/10.1038/srep25636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901192/
https://www.ncbi.nlm.nih.gov/pubmed/27173134
http://dx.doi.org/10.1038/srep25636

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