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Improving analytical methods for protein-protein interaction through implementation of chemically inducible dimerization
When investigating interactions between two proteins with complementary reporter tags in yeast two-hybrid or split GFP assays, it remains troublesome to discriminate true- from false-negative results and challenging to compare the level of interaction across experiments. This leads to decreased sens...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901268/ https://www.ncbi.nlm.nih.gov/pubmed/27282591 http://dx.doi.org/10.1038/srep27766 |