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Validity of leptin receptor-deficiency (db/db) type 2 diabetes mellitus mice as a model of secondary osteoporosis

This study aimed to evaluate the validation of the leptin receptor-deficient mice model for secondary osteoporosis associated with type 2 diabetes mellitus (T2DM) at bone micro-architectural level. Thirty three 36-week old male mice were divided into four groups: normal control (db/m) (n = 7), lepti...

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Detalles Bibliográficos
Autores principales: Huang, Le, You, Yong-ke, Zhu, Tracy Y, Zheng, Li-zhen, Huang, Xiao-ru, Chen, Hai-yong, Yao, Dong, Lan, Hui-yao, Qin, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901274/
https://www.ncbi.nlm.nih.gov/pubmed/27283954
http://dx.doi.org/10.1038/srep27745