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Nifurtimox Is Effective Against Neural Tumor Cells and Is Synergistic with Buthionine Sulfoximine

Children with aggressive neural tumors have poor survival rates and novel therapies are needed. Previous studies have identified nifurtimox and buthionine sulfoximine (BSO) as effective agents in children with neuroblastoma and medulloblastoma. We hypothesized that nifurtimox would be effective agai...

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Detalles Bibliográficos
Autores principales: Du, Michael, Zhang, Linna, Scorsone, Kathleen A., Woodfield, Sarah E., Zage, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901277/
https://www.ncbi.nlm.nih.gov/pubmed/27282514
http://dx.doi.org/10.1038/srep27458