Single Cell Proteolytic Assays to Investigate Cancer Clonal Heterogeneity and Cell Dynamics Using an Efficient Cell Loading Scheme

Proteolytic degradation of the extracellular matrix (ECM) is critical in cancer invasion, and recent work suggests that heterogeneous cancer populations cooperate in this process. Despite the importance of cell heterogeneity, conventional proteolytic assays measure average activity, requiring thousa...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Chih, Cheng, Yu-Heng, Ingram, Patrick, Yoon, Euisik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901291/
https://www.ncbi.nlm.nih.gov/pubmed/27283981
http://dx.doi.org/10.1038/srep27154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901291/
https://www.ncbi.nlm.nih.gov/pubmed/27283981
http://dx.doi.org/10.1038/srep27154

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