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Transient ECM protease activity promotes synaptic plasticity

Activity-dependent proteolysis at a synapse has been recognized as a pivotal factor in controlling dynamic changes in dendritic spine shape and function; however, excessive proteolytic activity is detrimental to the cells. The exact mechanism of control of these seemingly contradictory outcomes of p...

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Detalles Bibliográficos
Autores principales: Magnowska, Marta, Gorkiewicz, Tomasz, Suska, Anna, Wawrzyniak, Marcin, Rutkowska-Wlodarczyk, Izabela, Kaczmarek, Leszek, Wlodarczyk, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901294/
https://www.ncbi.nlm.nih.gov/pubmed/27282248
http://dx.doi.org/10.1038/srep27757