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Mechanisms of PDGF siRNA-mediated inhibition of bone cancer pain in the spinal cord

Patients with tumors that metastasize to bone frequently suffer from debilitating pain, and effective therapies for treating bone cancer are lacking. This study employed a novel strategy in which herpes simplex virus (HSV) carrying a small interfering RNA (siRNA) targeting platelet-derived growth fa...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Liu, Jia, He, Mu, Liu, Ran, Belegu, Visar, Dai, Ping, Liu, Wei, Wang, Wei, Xia, Qing-Jie, Shang, Fei-Fei, Luo, Chao-Zhi, Zhou, Xue, Liu, Su, McDonald, JohnW., Liu, Jin, Zuo, Yun-Xia, Liu, Fei, Wang, Ting-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901320/
https://www.ncbi.nlm.nih.gov/pubmed/27282805
http://dx.doi.org/10.1038/srep27512