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Dyslipidemia causes overestimation of plasma mitotane measurements

Mitotane (o,p′-DDD) is the standard treatment for advanced adrenocortical carcinoma (ACC). Monitoring of plasma mitotane levels is recommended to look for a therapeutic window between 14 and 20mg/L, but its positive predictive value requires optimization. We report the case of an ACC patient with a...

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Detalles Bibliográficos
Autores principales: Paci, Angelo, Hescot, Ségolène, Seck, Atmane, Jublanc, Christel, Mercier, Lionel, Vezzosi, Delphine, Drui, Delphine, Quinkler, Marcus, Fassnacht, Martin, Bruckert, Eric, Lombès, Marc, Leboulleux, Sophie, Broutin, Sophie, Baudin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901334/
https://www.ncbi.nlm.nih.gov/pubmed/27298727
http://dx.doi.org/10.1530/EDM-15-0135