Secretagogin affects insulin secretion in pancreatic β-cells by regulating actin dynamics and focal adhesion

Secretagogin (SCGN), a Ca(2+)-binding protein having six EF-hands, is selectively expressed in pancreatic β-cells and neuroendocrine cells. Previous studies suggested that SCGN enhances insulin secretion by functioning as a Ca(2+)-sensor protein, but the underlying mechanism has not been elucidated....

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Detalles Bibliográficos
Autores principales: Yang, Seo-Yun, Lee, Jae-Jin, Lee, Jin-Hee, Lee, Kyungeun, Oh, Seung Hoon, Lim, Yu-Mi, Lee, Myung-Shik, Lee, Kong-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901359/
https://www.ncbi.nlm.nih.gov/pubmed/27095850
http://dx.doi.org/10.1042/BCJ20160137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901359/
https://www.ncbi.nlm.nih.gov/pubmed/27095850
http://dx.doi.org/10.1042/BCJ20160137

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