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Recombinant Lactococcus lactis NZ9000 secretes a bioactive kisspeptin that inhibits proliferation and migration of human colon carcinoma HT-29 cells

BACKGROUND: Proteinaceous bioactive substances and pharmaceuticals are most conveniently administered orally. However, the facing problems are the side effects of proteolytic degradation and denaturation in the gastrointestinal tract. In recent years, lactic acid bacteria (LAB) have been verified to...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Li, Angdi, Zuo, Fanglei, Yu, Rui, Zeng, Zhu, Ma, Huiqin, Chen, Shangwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901401/
https://www.ncbi.nlm.nih.gov/pubmed/27287327
http://dx.doi.org/10.1186/s12934-016-0506-7