Altered excitatory-inhibitory balance within somatosensory cortex is associated with enhanced plasticity and pain sensitivity in a mouse model of multiple sclerosis

BACKGROUND: Chronic neuropathic pain is a common symptom of multiple sclerosis (MS). MOG(35–55)-induced experimental autoimmune encephalomyelitis (EAE) has been used as an animal model to investigate the mechanisms of pain in MS. Previous studies have implicated sensitization of spinal nociceptive n...

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Detalles Bibliográficos
Autores principales: Potter, Liam E., Paylor, John W., Suh, Jee Su, Tenorio, Gustavo, Caliaperumal, Jayalakshmi, Colbourne, Fred, Baker, Glen, Winship, Ian, Kerr, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901403/
https://www.ncbi.nlm.nih.gov/pubmed/27282914
http://dx.doi.org/10.1186/s12974-016-0609-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901403/
https://www.ncbi.nlm.nih.gov/pubmed/27282914
http://dx.doi.org/10.1186/s12974-016-0609-4

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