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Expression of 5α- and 5β-reductase in spinal cord and muscle of birds with different courtship repertoires

BACKGROUND: Through the actions of one or more isoforms of the enzyme 5α-reductase in many male reproductive tissues, circulating testosterone (T) undergoes metabolic conversion into 5α-dihydrotestosterone (DHT), which binds to and activates androgen receptors (AR) with greater potency than T. In bi...

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Detalles Bibliográficos
Autores principales: Fuxjager, Matthew J., Schuppe, Eric R., Hoang, John, Chew, Jennifer, Shah, Mital, Schlinger, Barney A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901407/
https://www.ncbi.nlm.nih.gov/pubmed/27293470
http://dx.doi.org/10.1186/s12983-016-0156-y