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Failure of a patient-derived xenograft for brain tumor model prepared by implantation of tissue fragments

BACKGROUND: With the continuing development of new anti-cancer drugs comes a need for preclinical experimental models capable of predicting the clinical activity of these novel agents in cancer patients. However existing models have a limited ability to recapitulate the clinical characteristics and...

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Detalles Bibliográficos
Autores principales: Kim, Kyung-Min, Shim, Jin-Kyoung, Chang, Jong Hee, Lee, Ji-Hyun, Kim, Se-Hoon, Choi, Junjeong, Park, Junseong, Kim, Eui-Hyun, Kim, Sun Ho, Huh, Yong-Min, Lee, Su-Jae, Cheong, Jae-Ho, Kang, Seok-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901492/
https://www.ncbi.nlm.nih.gov/pubmed/27293382
http://dx.doi.org/10.1186/s12935-016-0319-0