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Failure of a patient-derived xenograft for brain tumor model prepared by implantation of tissue fragments
BACKGROUND: With the continuing development of new anti-cancer drugs comes a need for preclinical experimental models capable of predicting the clinical activity of these novel agents in cancer patients. However existing models have a limited ability to recapitulate the clinical characteristics and...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901492/ https://www.ncbi.nlm.nih.gov/pubmed/27293382 http://dx.doi.org/10.1186/s12935-016-0319-0 |