Fingolimod promotes peripheral nerve regeneration via modulation of lysophospholipid signaling

BACKGROUND: The lysophospholipids sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) are pleiotropic signaling molecules with a broad range of physiological functions. Targeting the S1P(1) receptor on lymphocytes with the immunomodulatory drug fingolimod has proven effective in the treatm...

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Detalles Bibliográficos
Autores principales: Szepanowski, Fabian, Derksen, Angelika, Steiner, Irina, Meyer zu Hörste, Gerd, Daldrup, Thomas, Hartung, Hans-Peter, Kieseier, Bernd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901498/
https://www.ncbi.nlm.nih.gov/pubmed/27283020
http://dx.doi.org/10.1186/s12974-016-0612-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901498/
https://www.ncbi.nlm.nih.gov/pubmed/27283020
http://dx.doi.org/10.1186/s12974-016-0612-9

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