Asymmetric α-amination of 3-substituted oxindoles using chiral bifunctional phosphine catalysts

A highly enantioselective α-amination of 3-substituted oxindoles with azodicarboxylates catalyzed by amino acids-derived chiral phosphine catalysts is reported. The corresponding products containing a tetrasubstituted carbon center attached to a nitrogen atom at the C-3 position of the oxindole were...

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Detalles Bibliográficos
Autores principales: Jin, Qiao-Wen, Chai, Zhuo, Huang, You-Ming, Zou, Gang, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902028/
https://www.ncbi.nlm.nih.gov/pubmed/27340464
http://dx.doi.org/10.3762/bjoc.12.72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902028/
https://www.ncbi.nlm.nih.gov/pubmed/27340464
http://dx.doi.org/10.3762/bjoc.12.72

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