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A cross-metathesis approach to novel pantothenamide derivatives

Pantothenamides are known for their in vitro antimicrobial activity. Our group has previously reported a new stereoselective route to access derivatives modified at the geminal dimethyl moiety. This route however fails in the addition of large substituents. Here we report a new synthetic route that...

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Detalles Bibliográficos
Autores principales: Guan, Jinming, Hachey, Matthew, Puri, Lekha, Howieson, Vanessa, Saliba, Kevin J, Auclair, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902030/
https://www.ncbi.nlm.nih.gov/pubmed/27340487
http://dx.doi.org/10.3762/bjoc.12.95