Modular synthesis of the pyrimidine core of the manzacidins by divergent Tsuji–Trost coupling

The design, development and application of an efficient procedure for the concise synthesis of the 1,3-syn- and anti-tetrahydropyrimidine cores of manzacidins are reported. The intramolecular allylic substitution reaction of a readily available joint urea-type substrate enables the facile preparatio...

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Detalles Bibliográficos
Autores principales: Bretzke, Sebastian, Scheeff, Stephan, Vollmeyer, Felicitas, Eberhagen, Friederike, Rominger, Frank, Menche, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902044/
https://www.ncbi.nlm.nih.gov/pubmed/27340499
http://dx.doi.org/10.3762/bjoc.12.107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902044/
https://www.ncbi.nlm.nih.gov/pubmed/27340499
http://dx.doi.org/10.3762/bjoc.12.107

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